Aubrey de Grey — English Author born on April 20, 1963,

Aubrey David Nicholas Jasper de Grey is an English author and biomedical gerontologist, currently the Chief Science Officer of the SENS Research Foundation. He is editor-in-chief of the academic journal Rejuvenation Research, author of The Mitochondrial Free Radical Theory of Aging and co-author of Ending Aging . He is known for his view that medical technology may enable human beings alive today to live indefinitely... (wikipedia)

My approach is to start from the straightforward principle that our body is a machine. A very complicated machine, but none the less a machine, and it can be subjected to maintenance and repair in the same way as a simple machine, like a car.
If you look at winners of the Nobel Prize in biology, you'll find a fair smattering of people who don't know how to work a pipette.
Wikipedia was a big help for science, especially science communication, and it shows no sign of diminishing in importance.
There's no such thing as ageing gracefully. I don't meet people who want to get Alzheimer's disease, or who want to get cancer or arthritis or any of the other things that afflict the elderly. Ageing is bad for you, and we better just actually accept that.
The biggest handicap in research is an ability to think outside the box. The handicap is being encumbered by all the conventional wisdom in a given field.