After young Riley is uprooted from her Midwest life and moved to San Francisco, her emotions - Joy, Fear, Anger, Disgust and Sadness - conflict on how best to navigate a new city, house, and school.

Bing Bong: Take her to the moon for me. Okay?
Sadness: Crying helps me slow down and obsess over the weight of life's problems.
Anger: [seeing slices of pizza with only broccoli on top]
Anger: Congratulations San Francisco, you've ruined pizza! First the Hawaiians, and now YOU!
[from trailer]
Riley: [Disgust pushed a button and pulls a short lever] School was great, all right?
Fear: What was that? I though you said we were gonna "act casual".
Mom: Riley! Is everything okay?
[Riley sighs]
Father's Fear: Sir, she just rolled her eyes at us!
Father's Anger: All right, make a show of force, I don't want to have to put the foot down.
Father's Fear: No! Not the foot...
Dad: Riley, I do not like this new attitude.
Anger: Oh, I show you attitude, old man!
Fear: No! No, no, no! Breath!
[He gets punched by Anger, and Anger pushes a red button hard]
Riley: What is your problem? Just leave me alone!
Father's Fear: Sir, reporting high levels of sass!
Father's Anger: Take it to DEFCON 2!
Father's Fear: DEFCON 2!
Dad: I don't know where this disrespectful attitude came from.
Anger: You want a piece of this, Pops?
Riley: Yeah, well...
Father's Anger: Prepare the foot!
Father's Fear: Keys to safety position!
[Father's emotions unlocks the foot and Father Fear is about to ready to hit the red button]
Father's Fear: Ready to launch on your command, sir!
Riley: [Anger hardly yells and pulls the lever as the explosion on the top of his head is on fire] Just shut up!
Father's Anger: Fire!
[Father Fear pushes the red button that releases the foot down]
Dad: That's it! Go to your room!
Father's Fear: The foot is down. The foot is down. Whoo!
[Father's emotions cheered]
Father's Anger: Good job, gentleman. That could have been a disaster.
Mother's Sadness: Well, that was a disaster.
Sadness: [in trailer; Joy is walking through Riley's mind, carrying the memory spheres] It's long term memory... you'll get lost in there.
Joy: [calling over her shoulder] C'mon! Think positive!
Sadness: Okay...
[pause]
Sadness: I'm positive that you'll get lost in there!
Fear: Maybe it was a bear?
Disgust: There are no bears in San Francisco.
Anger: I saw a really hairy guy, he looked like a bear.
[from trailer]
Joy: Come on, group hug! You too, Anger.
Anger: Don't touch me.
Mind Worker Cop Jake: So, you're saying your husband was blown away by an elephant. Was he with anyone?
Mind Worker Cop Jake: Yes! And there she is!
[Joy runs through the Cloud Woman, causing her to disappear]
Mind Worker Cop Jake: Hey, come back here!
Mind Worker Cop: Forget it, Jake.
[He removes his sunglasses]
Mind Worker Cop: It's Cloudtown.
Joy: All these facts and opinions look the same. I can't tell them apart.
Bing Bong: Happens to me all the time. Don't worry about it.
Bing Bong: [Seeing a memory image of 11-year-old Riley] Whoa. Is this Riley?
[Joy looks at the image and nods]
Bing Bong: She's so big now. She won't fit in my rocket. How're we gonna get to the moon?"
Joy: Oh, it's that time in the twisty tree, remember? The hockey team showed up and Mom and Dad were there cheering. Look at her, having fun and laughing. It's my favorite.
Sadness: I love that one, too.
Joy: Atta girl! Now you're getting it!
Sadness: Yeah, it was the day the Prairie Dogs lost the big playoff game. Riley missed the winning shot. She felt awful. She wanted to quit. Sorry, I went sad again, didn't I?
Fear: All right! We did not die today, I call that an unqualified success.
Clown's Joy: Six years of drama school... for this.
[when trying to get out of The Dump, Joy looks at the blue Core Memory and looks at a forgotten memory]
Joy: You remember how she used to stick her tongue out when she was colouring?
[Joy picks another forgotten memory up and looks at it]
Joy: I could listen to her stories, all day.
[Joy picks up a third one]
Joy: I just wanted Riley to be happy...
[holding the three forgotten memories and the blue Core Memory, she breaks down into tears]
[Riley is on the verge of tears after attempting to run away back to Minnesota after feeling very homesick]
Riley: I... I know you don't want me to, but I miss home. I miss Minnesota. You need me to be happy, but I want my old friend, and my hockey team. I wanna go home. Please don't be mad.
[Riley's mother and father stare sadly at their daughter]
Mom: Oh, sweetie...
Dad: Were not mad. You know what? I miss Minnesota too. I miss the woods where we took hikes.
Mom: And the backyard where we used to play.
Dad: Spring Lake, where you used to skate.
[Riley breaks down in tears]
Dad: Come here.
[Riley, her mother, and her father all embrace in a group hug, consoling Riley]
Anger: I say we lock ourselves in our room and use that one swear word we know. It's a good one!
Dad: [Trying to feed Riley broccoli] Here we go. All right, open.
Joy: Hmm... this looks new.
Fear: Think it's safe?
Sadness: What is it?
Disgust: Okay, caution, there is a dangerous smell, people. Hold on, what is that? That is not brightly colored or shaped like a dinosaur, hold on guys... it's... broccoli!
[presses buttons]
Riley: Yukee!
[flips bowl of broccoli on Dad]
Disgust: Well, I just saved our lives. Yeah, you're welcome.
Dad: Riley, if you don't eat your dinner you're not gonna get any dessert.
Anger: Wait, did he just say we couldn't have dessert?
[paces angrily]
Anger: So that's how you wanna play it, old man? No dessert? Oh sure, we'll eat our dinner, right after you eat THIS!
[presses buttons]
Riley: [starts crying and screaming]
Dad: Riley, Riley, here comes an airplane.
Anger: Oh, airplane. We got an airplane, everybody.
Joy, Fear, Sadness, Disgust: Ooooh!
[Riley eats broccoli]
[from trailer]
Joy: I'm Joy, this is Sadness, that's Anger, this is Disgust.
Disgust: Ugh...
Joy: And that's Fear.
Fear: Ahhh! Look out!
Anger: [after Joy and Sadness are ejected] Can I use that swear word now?
Sadness: I'm too sad to walk. Just give me a few... hours.
Fear: [Watching Riley's dream] Let me guess, she forgot to put on her pants.
Girl: Look, the new girl has no pants on!
Fear: Called it!
Joy: Hey, look! The Golden Gate Bridge! Isn't that great? It's not made out of solid gold like we thought, which is kind of a disappointment, but still!
Fear: I sure am glad you told me earthquakes are a myth Joy, otherwise i'd be terrified right now.
Joy: Uh... yeah...
Additional Voices: [During dream sequence] Eat us! We're organic!
[Joy makes Riley laugh for the first time]
Joy: [voiceover] It was amazing! Just Riley and me, forever.
[Riley suddenly starts crying]
Joy: [voiceover] Um, for thirty-three seconds.
[Joy looks down, and sees Sadness operating Riley's control panel]
Sadness: I'm Sadness.
Joy: Oh, hello! Uh, I'm Joy. So, could I just... If you could... I just wanna fix that. Thanks.
[Joy nudges Sadness aside and tries to push the button, only for Sadness to nudge back and push the button again]
Joy: [voiceover] And that was just the beginning! Headquarters only got more crowded from there.
[as Riley is about to become permanently depressed, Joy and Sadness arrive back at Headquarters by flinging themselves into the window. They manage to hold on for dear life]
Disgust: It's Joy!
[Anger runs off to grab a chair]
Anger: Stand back!
[Anger violently throws the chair at the window, to no avail]
Disgust: That worked.
[Anger begins to get irritated and his head begins to smoulder]
Anger: Well, what would you do if you're so smart?
[Disgust smiles, realizing the opportunity]
Disgust: I'd tell you, but you're too dumb to understand.
Anger: WHAT?
Disgust: Of course your tiny brain is confused. Guess I'LL just have to dumb it down to your level!
[as Anger's head begins to smoulder even more, he looks at Disgust in complete rage]
Disgust: Sorry I don't speak moron as well as you, but lemme try! Duuuuuhhhhhh!
[Anger begins to scream in rage as flames erupt from the top of his head]
Anger: ARRRRRRRRRRHHHHHHHHHHH!
[Disgust flips on a visor helmet and holds Anger against the window. The flames shooting out of the top of his head break the window. Fear and Disgust help Joy and Sadness inside]
[first lines]
Joy: Do you ever look at someone and wonder, "What is going on inside their head?" Well, I know. Okay, I know Riley's head.
[Joy and Bing Bong have fallen into the Memory Dump and are suck down there, doomed to be forgotten forever. Joy tried fruitlessly to climb up the piles of old memories to get out]
Bing Bong: Joy? Joy, what are you doing, would ya stop it, please?
[Joy ignores his pleas and keeps trying to get out, once again, to no avail]
Bing Bong: DON'T YA GET IT JOY? WE'RE STUCK DOWN HERE! We're forgotten...
[Joy pauses to realize her situation. In the background, the discarded sad core memory of Riley breaking down into tears on her first day at school begins to play]
Riley: [in the memory orb] We... used to play tag... and stuff...
[Joy walks over to the memory, and holds it sombrely]
Riley: [in the memory orb] But... everything is different now. Since we moved...
[the memory keeps playing the "video" of Riley's emotional breakdown at school. Joy keeps staring at the memory orb, in complete helpless despair. She sits down and begins to stifle tears. The sound of a discarded memory of Riley happily coloring as a toddler begins to play next to Joy, who picks it up and looks at it with a sad smile before tearing up]
Joy: Do you remember how she used to stick her tongue out when she was colouring?
[Joy continues to fight back tears. She picks up another memory orb, this time of a younger Riley telling a story to her parents]
Joy: I could listen to her stories, all day...
[Joy picks up another memory of Riley playing in her backyard as a toddler. Joy's eyes well up with tears, but she keeps holding back]
Joy: I just wanted Riley to be happy...
[Joy picks up the sad core memory of Riley crying in school. As he looks at it, she begins to sob, and completely breaks down into hopeless tears while Bing Bong sadly looks on. Joy's tears fall onto the happy memory orb of Riley after the Prairie Dog hockey game. As Joy wipes the tear off of it, she scrolls through the memory to see it was previously a sad memory turned happy. The sad portion consists of Riley sitting sadly with her parents on a tree branch. Curiously, Joy "rewinds" the memory to the point where Mom and Dad came to Riley to comfort her. Joy begins to hear Sadness's description of the memory in her head]
Sadness: [v.o] It was the day the Prairie Dogs lost the big playoff game. Riley missed the winning shot, she felt awful. She wanted to quit.
[Joy scrolls through the memory to see the blue sad memory of her and her parents turn a happy yellow when Riley's friends come to cheer her on]
Joy: Sadness... Mom and Dad... the team. They came to help... because of Sadness.
Disgust: What's "poo-ber-tee"?
[Joy begins the new day by waking up all the emotions with an accordion]
Joy: Hello! Did I wake you?
Anger: Did you have to play that?
Joy: Well, I have to practice! And I don't think of it so much as playing more so as "hugging"!
[Joy lovingly hugs the accordion before tossing it away. She rushes down the stairs in excitement]
Joy: Okay! First day of school! Very very exciting! I was up late last night figuring out a new plan. Here it is!
[Fear walks by writing on a notepad]
Joy: Fear! I need a list of possible negative outcomes on the first day at a new school?
Fear: Way ahead of ya there! Does anyone know how to spell "meteor"?
[Disgust walks by putting on makeup]
Joy: Disgust! Make sure Riley stands out today, but also blends in!
Disgust: When I'm through, Riley will look so good, the other kids will look at their own outfits and barf!
Joy: Joy!
[Joy steps aside and begins to talk to "herself"]
Joy: Yes, Joy?
Joy: You'll be in charge of the console, keeping Riley happy all day long! And did I mention I love your dress, its adorable?
[Joy begins to happily twirl around]
Joy: Oh, this old thing? Thank you so much! I love the way it twirls!
Sadness: Aww, participation award.
Anger: This is ridiculous! We can't even get a good night's sleep anymore.
[Anger grabs an idea bulb from the shelf]
Anger: Time to take action! Stupid Mom and Dad hadn't've moved us, none of this would have happened. Who's with me?
[Anger gestures the idea to Fear]
Fear: Um... mmmmmmmmm... Nnnnnnnn... no.
[Anger gestures the idea to Disgust]
Disgust: ...Yeah, okay. Let's do it.
[Anger puts the idea bulb into the console. Outside, Riley gets the idea and opens up her laptop]
Anger: She took it. There is no turning back.
Disgust: So... how are we going to get to Minnesota from here?
Anger: Well, why don't we go down to the elephant lot and rent an elephant?
Fear: Hey! That sounds nice!
Anger: WE'RE TAKING THE BUS, NITWIT!
[Riley is looking up bus information on the San Francisco Greyhound Bus website]
Anger: There is a bus leaving tomorrow. Perfect!
Disgust: A ticket costs money. How do we get money?
Anger: Mom's purse.
[Disgust gasps in horror]
Disgust: You wouldn't!
Anger: Oh, but I would. Where was it we saw it last?
[Anger recalls a memory of where the purse was. However, the memory of the Triple Dent Gum commercial comes up and its annoying song begins to play. Anger immediately becomes annoyed and slams on the console, startling Fear]
Anger: NO!
Sadness: Remember the funny movie where the dog died?
[Anger has just gotten an idea to make Riley happy again]
Anger: Wait a minute. WAIT A MINUTE!
[He goes over to the shelf and browses for a second before grabbing an idea bulb]
Anger: AH-HA! Ho ho ho!
Fear: What is it?
Anger: Oh nothing. Just the best idea ever!
Disgust: What?
Anger: All the good core memories were made in Minnesota. Ergo, we go back to Minnesota and make more. TA DA!
Fear: Wait wait wait, you're saying we... run away?
Anger: Well, I wouldn't call it that, I'd call it the "Happy Core Memory Development Program"!
Fear: You can't be serious!
Anger: Hey! Our life was perfect before Mom and Dad decided to move to... San Fran-State Town!
Fear: But... But I mean, it's just so drastic...
Anger: Need I remind you of how great things were there?
[Anger walks over to the console and begins typing to call up a memory]
Anger: Our room... Our backyard... Our friends!
[a memory comes up. It is the TripleDent Gum commercial. Its annoying jingle begins to play]
Anger: DID I ASK FOR THE GUM COMMERCIAL?
[Anger slams down on the console, ending the memory's playback abruptly]
Anger: Anyway, it was better, that's my point.
Bing Bong: D, A, N, G, E, R, SHORTCUT!
Joy: Hey! Hey, look at me. Did you mean what you said before?
Riley's Imaginary Boyfriend: I would die for Riley. I would die for Riley.
Joy: Yeah, yeah, okay, haircut. Time to prove it!
[stuffs him in a bag]
[as Riley lies in her sleeping bag, a truck loudly drive by outside. The headlights can be seen shining through the room. Riley hides under the sleeping bag in fear]
Fear: What was that? Was it a bear? It's a bear!
Disgust: [Fear begins to franticly push buttons on the console]
Disgust: There are no bears in San Francisco.
Anger: I saw a really hair guy, he looked like a bear.
Fear: Oh, I'm so jumpy, me nerves are shot!
Disgust: Ew! I don't wanna hear about your nerves!
Anger: I'll tell you what it is, this move has been a bust.
Fear: That's what I've been telling you guys! There are at least thirty-seven things for Riley to be scared of right now.
Disgust: This smell alone is enough to make her gag!
Anger: I can't believe mom and dad moved us here!
Joy: Look! I get it, you guys have concerns. But we've been through worse. Tell ya what , let's make a list of all the things Riley should be happy about!
Anger: Fine. Let's see, this house stinks, our room stinks...
Disgust: Pizza is weird here...
Sadness: Our friends are back home...
Fear: And all of our stuff is in the missing van!
Joy: Oh, come on! It could be worse...
Disgust: Yeah Joy, we could be lying on the dirty floor in a bag.
[Riley is seen doing exactly that, lying on the floor in a sleeping bag and two pillows]
Joy: Ok, I admit it. We had a rough start, but think of all the good things that...
Anger: No Joy, there is absolutely no reason for Riley to be happy right now. Let us handle it.
Fear: I'd say we skip school tomorrow and lock ourselves in the bedroom.
Disgust: We have no clean clothes, I mean no one should see us.
Fear: [Sadness clings to Joy]
Sadness: We could cry until we can't breathe.
Anger: We should lock the door and scream that curse word we know! It's a good one!
Anger: [Upon seeing the bumper-to-bumper traffic in San Francisco] These are my kind of people!