A television reporter and her cameraman are trapped inside a building quarantined by the CDC after the outbreak of a mysterious virus which turns humans into bloodthirsty killers.

Yuri Ivanov: They won't let us out.
Angela Vidal: [after witnessing Bernard be killed by a CDC Sniper] Scott... They're not gonna let us out of here alive, are they?
Scott Percival: No... I don't think so.
Scott Percival: The door closed behind me.
Angela Vidal: Did you get that?
Scott Percival: Yeah.
Griffin: [camera is on him in the shower] You know, I hope that's a wide-angle lens.
Jake: So, let's just pretend you're five years old and on fire.