A quadriplegic ex-homicide detective and his female partner try to track down a serial killer who is terrorizing New York City.

Paulie: If you were any more wound up you'd be a timex.
Rhyme: There are five basic contaminants in a crime scene. I'll skip to the worse one. Other cops.
Lincoln Rhyme: Destiny is what we make it
Amelia: What, you think that because of your condition you have the right to boss people around? I'm sorry, but that is truly pathetic.
Rhyme: Truly?
Amelia: Damn right, truly.
Rhyme: Do you know who I am?
Amelia: I read your manual at the academy.
Rhyme: Yeah? What did you think of it?
Amelia: I'm not a book critic, sir.
Rhyme: [Amelia caresses a sleeping Rhyme's hand] There are laws against molesting the handicapped, you know.
[he awakens]
Amelia: Yeah?
[laughs]
Amelia: Smells like manure down here. Ortiz knows his shit!
Richard Thompson: Do you know what happens to a cop in prison? You are brutalised every single day over and over... you become a human toilet.
Captain Howard Cheney: You got a smart mouth, and it's gonna get you in trouble someday.
Thelma: Yeah, and it also may bite your ass if you don't stop tryin' to aggravate my patient!
Eddie Ortiz: It's everyone's worst nightmare; you get into a cab and there's some psycho from Jersey behind the wheel.
Richard Thompson: [ranting] I gave you so many clues and you failed... you fucking failed.
Amelia: Shit! Cheney's here.
[puts the evidences into her pocket]
Captain Howard Cheney: You talking to Rhyme on that thing? Give me the radio. Now, listen, Linc. This is Cheney, man. What the hell do you think you're doing? Stealing evidence is a goddamn felony. You know that.
Lincoln Rhyme: To my understanding, there's no chain of evidence voucher.
Captain Howard Cheney: Oh, yeah? Well, I got some news for you. You are not a cop anymore. You understand that? What you are is a fucking meddling cripple. Now, I'm gonna place your little gofer here under arrest. You don't mind that, do ya? Lock her up.
[looks back and finds Amelia gone]
Paulie: Where'd she go?
Detective Kenny Solomon: You were a model.
Amelia: Yeah, when I was a kid.
Detective Kenny Solomon: Kid model to street cop... there's a leap.
[pause]
Detective Kenny Solomon: For whatever it's worth... I thought what you did today was pretty damn terrific.
Amelia: [shows evidence bags] Maybe this'll help.
Lincoln Rhyme: Cheney will have your badge for that.
Amelia: Well, he wouldn't give me a chain of custody voucher, so what could I do?
Lincoln Rhyme: You could bring it back to him.
Amelia: The man is a living monument to ineptitude.
Lincoln Rhyme: True. Let's take a look.
Lincoln Rhyme: Whatever happened to your father doesn't mean it's gonna happen to you. You're a great cop. You'd make a terrific detective. It's a gift. Don't throw it away.
Captain Howard Cheney: You the one who stopped the train?
Amelia: Yes, sir. I thought it would disturb physical evidence.
Captain Howard Cheney: So, why not shut down Grand Central while you're at it, hmm, Patrolman Donahue? Is that right?
Amelia: Donaghy.
Captain Howard Cheney: A rookie, I take it?
Amelia: No, sir.
Captain Howard Cheney: Pretty dumb.
Lincoln Rhyme: Nitrogen rich, explosive carbons, where do you find those in New York City?
Paulie: Bomb sites, shooting ranges.
Amelia: Maybe an old fort or an armory?
Eddie Ortiz: Let's not forget the shit factor, guys.
Lincoln Rhyme: The what?
Eddie Ortiz: Manure becomes a nitrate when it's aged.
Lincoln Rhyme: That's true. And you got cow bones, huh? Old cow bones, old manure. Turn of the century. Cows, farms... pastures, rats... dead cows. Where do you find... In stockyards... slaughterhouses, that's what we want to look for.
Lincoln Rhyme: Two things. First, you did a hell of a job locating the evidence. There's no question the perp knows forensics.
[pause]
Lincoln Rhyme: Now, as for the other thing... the... you know, the victim's hands, well, maybe, uh... maybe it was too much to handle, so we'll just forget it.
Amelia: Is that your version of an apology?
Lincoln Rhyme: An apology? Is that why you came over here?
Amelia: You really are a piece of work.
Lincoln Rhyme: Well, aren't we a pair?... I think you're terrific.
Lincoln Rhyme: I want you to work the case with us.
Amelia: It's not my area.
Lincoln Rhyme: Are you being modest or are you... a little uneasy about doing some real police work?
Thelma: Just give it a few seconds to work. Come on, breathe with me. Breathe with me, Rhyme. Rhyme! Come on, now... Hang on, Rhyme. Hang on, man.
Amelia: Is he gonna make it?
Thelma: If he does, he won't be happy.
Amelia: What are you talking about?
Thelma: He's already finalized arrangements to self-terminate... He's got some doctor friend to help with his "final transition" as he calls it.
Amelia: But suicide? I mean...
Thelma: It's the seizures. Any one of them could put him into a vegetative state. That's what he fears more than anything.
Lincoln Rhyme: Pull up a chair. I want you to tell me everything you know about the crime scene.
Amelia: Basically, you saw my report.
Lincoln Rhyme: I read your report. I wanna know what you felt. What you feel... in the deepest recesses of your senses.
Amelia: You are in love with the sound of your own voice, aren't you?
Lincoln Rhyme: No, it's your voice I yearn to hear. Pull up a chair. I won't bite you.
Lincoln Rhyme: How is your mother?
Eddie Ortiz: Oh, God, she's 76, and she's schtupping some guy named Morris. Can you believe it?
Lincoln Rhyme: God bless her.
Eddie Ortiz: It's Morris I'm worried about. He's 76, with a tricky ticker and an active pecker.
Lincoln Rhyme: Sounds like you're starting to enjoy this work.
Lincoln Rhyme: All right, this is what I want you to do. We're gonna need those handcuffs really. It's probably our best chance for good prints.
Amelia: The M.E. can remove them when they get here.
Lincoln Rhyme: The M.E. is all thumbs really. They'll mess up the prints. Look in the suitcase. There's a small saw.
Amelia: [finds the saw] Okay.
Lincoln Rhyme: I want you to saw her hands off at the wrist line. We gotta have those cuffs for prints.
Amelia: [pause] I can't.
Lincoln Rhyme: Cut her hands off. We need the handcuffs.
Amelia: I can't. No.
Lincoln Rhyme: Saw off her hands, take off the cuffs.
Amelia: I can't.
Lincoln Rhyme: Listen to me. Saw off her h... We need those cuffs.
Amelia: I can't!
Lincoln Rhyme: Amelia, we need...
Amelia: No, fuck you!
Paulie: [Amelia drives the car screeching from lane to lane] Jesus Christ! I'd like to get there in one piece, if possible.
Lincoln Rhyme: Maybe... maybe he's trying to share the responsibility of these murders with us. If we don't figure out the clues in time, the blood's on our hands. If we don't find the victim in time, we're as responsible for the murders as he is.
Paulie: You okay?
Amelia: I'm fine. Wanna step aside so I can walk the grid?
Paulie: Yeah.
Amelia: Thelma told me about your plans for your "final transition."
Lincoln Rhyme: Cop to cop, that subject's not open to discussion. Why?... Would you miss me?
Amelia: Well, destiny's what we make it, right?
Lincoln Rhyme: Touche.
Amelia: Now, you seem to have your reasons for checking out. I just... I would have expected more from someone like you.
Lincoln Rhyme: Well, I might surprise you and... live forever.
Amelia: Nothing you could do would surprise me, Rhyme.
Richard Thompson: Some people win... some people lose... the game is over.
Amelia: I can't do this.
Lincoln Rhyme: You can do it. Yes, you can. Yesterday you stopped a train. You can do anything you want when you put your mind to it.
Amelia: Don't work me, Rhyme... Just tell me what to do next.
Lincoln Rhyme: Very slowly... walk the grid... one foot in front of the other. I want you to look around you now. Remember... crime scenes are three-dimensional... floors, walls and ceilings.
Lincoln Rhyme: Just trust me. Just follow those instincts you were born with. I'll be with you... every step of the way.
Lincoln Rhyme: [operating PC with his voice to see the unsolved homicide photos] Zoom. Same mark. Right. Zoom. Zoom. Zoom... Same messages. It's him... The perp was trying to make contact even then.
Amelia: But Cheney never put it together.
Amelia: Excuse me, but the victim was already dead when we arrived.
Captain Howard Cheney: And you, half-assed patrolman working a crime scene... those days are over. I'll take that evidence bag now, thank you.
Amelia: You can take it with a chain of custody voucher, sir.
Captain Howard Cheney: Are you out of your mind? Hmmm? Let's go. You're coming with us.
Amelia: What? Are you arresting me?
Captain Howard Cheney: You just get in the car, and keep your mouth shut to the press.
Richard Thompson: You wanna play?
[pause]
Richard Thompson: Shall we cut out your tongue, Mr, Rhyme? How 'bout your eye? Your eye... we'll just pop it right out of there. No. Let's leave that for now. You can watch me. You can watch me while I get you open, right down the middle.
[Rhyme mutters something]
Richard Thompson: What?... What?... What?