A boy genius and his comrades travel to different parallel universes, trying to find their way back home.

Quinn Mallory: [season five opening monologue] What if you found a portal to a parallel universe? What if you could Slide into a thousand different worlds? Where it's the same year, and you're the same person, but everything else is different. And what if you can't find your way home?
Prof. Maximillian P. Arturo: More power, Mr. Mallory!
Prof. Maximillian P. Arturo: That scoundrel! That intellectually impoverished knave wanted me to win his Nobel for him. As you can see, I told him nothing!
[points to sour looking face chalked on blackboard]
Quinn Michael Mallory: You are really starting to piss me off!
Quinn Michael Mallory: We have a plan. We just don't know what it is yet.
Rembrandt Lee "Crying Man" Brown: I didn't mind killing him. I might have a twinge of guilt about killing you, but then again, maybe not.
Quinn Mallory: [season one monologue/opening] What if you could find brand new worlds right here on Earth? Where anything is possible. Same planet, different dimension. I've found the gateway.
Rembrandt Brown: She's supposed to be ugly? The Kromaggs ever look in a mirror? Eye-eating freaks!
Prof. Maximillian P. Arturo: [after coffee is spilt all over him] Drink it, don't carry it, you idiot!
Rembrandt 'Crying Man' Brown: [season five opening monologue] What if you found a portal to a parallel universe? What if you could Slide into a thousand different worlds? Where it's the same year, and you're the same person, buy everything else is different. And what if you can't find your way home?
[a group of Amish-dressed people are coming to attack Colin Mallory]
Quinn Michael Mallory: Great! We're gonna get beat up by the cast of Witness!
Quinn Mallory: [season two opening monologue] What if you could travel to parallel worlds? The same year, the same Earth, only different dimensions. A world where the Russians rule America... or where your dreams of being superstar came true... or where San Francisco was a maximum-security prison. My friends and I found the gateway. Now the problem is... finding a way back home.