Haunted by the patients he failed to save, an extremely burned-out Manhattan ambulance paramedic fights to maintain his sanity over three fraught and turbulent nights.

Frank Pierce: I realised that my training was useful in less than ten percent of the calls, and saving lives was rarer than that. After a while, I grew to understand that my role was less about saving lives than about bearing witness. I was a grief mop. It was enough that I simply turned up.
Frank Pierce: I'd always had nightmares, but now the ghosts didn't wait for me to sleep.
Marcus: I rebuke the spirit of drugs in the name of Jesus. What's his name?
Drummer: I.B. Bangin'.
Marcus: What you mean I.B. Bangin'?
Drummer: I.B. Bangin'!
Marcus: What the hell kind of name is I.B. Bangin'?
Drummer: I don't know his real name.
I.B.'s Girlfriend: It's Frederick Smith.
Marcus: Okay, Freddy...
I.B.'s Girlfriend: It's Frederick.
Marcus: Okay, I.B. Bangin', we're gonna bring you back from the dead.
Griss: Don't make me take off my sunglasses!
Rose: It's not your fault. No one asked you to suffer. That was your idea.
Frank Pierce: Saving someone's life is like falling in love. The best drug in the world. For days, sometimes weeks afterwards, you walk the streets, making infinite whatever you see. Once, for a few weeks, I couldn't feel the earth - everything I touched became lighter. Horns played in my shoes. Flowers fell from my pockets. You wonder if you've become immortal, as if you've saved your own life as well. God has passed through you. Why deny it, that for a moment there - why deny that for a moment there, God was you?
Mary Burke: You have to be strong to survive in this city.
[Frank and Marcus are delivering a baby in a rundown building]
Frank Pierce: Oh Jesus, we'd better go. Call for backup. It's coming.
Marcus: My God, Frank, what the hell is that?
Frank Pierce: It's three legs.
Marcus: That's too many.
Frank Pierce: The streets are not like the ER. There's no walls, no controls.
Tom Wall: Frank, what are you doing back there?
Frank Pierce: I'm sick, Tom. I need a cure. Vitamin B cocktail, followed by an amp of glucose and a drop of adrenaline. Not as good as beer, but it's all I got.
Frank Pierce: You said if I came in late for another shift, you'd fire me.
Captain Barney: I'll fire you tomorrow.
Dr. Hazmat: I thought you said this guy was dead.
Frank Pierce: He got better.
Marcus: Don't tell me about the Good book now, son. I'll preach heaven and beat the hell outta you.
Dispatcher: You'll be going to the man who needs no introduction. Chronic caller of the year three straight and shooting for number four. The duke of drunk, the king of stink, our most frequent flier, Mr. Oh.
Frank Pierce: Tom, where are the Band-Aids? This IS an ambulance, isn't it?
Tom Wall: You okay?
Frank Pierce: Never felt better in my life, how are you?
Frank Pierce: Oh, I see. With all the poor people of this city who wanted only to live and were viciously murdered, you have the nerve to sit here, wanting to die, and not go through with it? You make me sick!
Frank Pierce: Taking credit when things go right doesn't work the other way.
Dispatcher: Twelve David, on the corner of Thirty-eight and Two you'll find a three car accident. Two taxis and a taxi. One-two Henry, 427 East Two-two, report of a very bad smell.
Marcus: Rule Number One: Don't get involved with patients. Rule Number Two: don't get involved with patients' daughters, now do you understand that?
Frank Pierce: What about Rule Number Three: Don't get involved with dispatchers named Love?
Marcus: Boy, you don't know nothin' bout Rule Number Three! Can't even begin to understand the complexities of that rule!
Marcus: I'm a true cocksman. I don't mix my seed. The only time I touch a white woman is when I'm holding her down for the police.
Tom Wall: Look up, Frank. Full moon. The blood's gonna run tonight. I can feel it. Our mission: to save lives.
Frank Pierce: Our mission is coffee, Tom. A shot of the bull, Puerto Rican espresso.
Tom Wall: Ten-four. El Toro de Oro! Blast off!
Frank Pierce: I gotta get a drink. Sobriety's killing me.
Marcus: The first step is love, the second is mercy.
Tom Wall: 66-Exterminator here. We like our coffee bloody!
Tom Wall: Frank, what do you know? It's you and me again tonight. The rough riders, tearing up the streets, just like old times. This old bus is a warrior, Frank. I have tried to kill her, but she will not die. I have a great respect for that.
Frank Pierce: [listening to the radio] Hey, it's Love!
Marcus: Yep, she only works when I'm workin'.
Frank Pierce: I heard you and Love went on a blind date.
Marcus: Yeah.
Frank Pierce: She hit you with a bottle?
Marcus: Why you gotta bring that up? She loved me like no woman ever has.
Griss: Griss cannot abide the funk tonight.
Marcus: Ever notice people who see shit are always crazy?
Dr. Hazmat: I'm gonna hafta intubate because the kid's mother won't sign the Do Not Resuscitate. Mercy killing doesn't translate well in Spanish.