In 1959, Truman Capote learns of the murder of a Kansas family and decides to write a book about the case. While researching for his novel In Cold Blood, Capote forms a relationship with one of the killers, Perry Smith, who is on death row.

Truman Capote: It's as if Perry and I grew up in the same house. And one day he stood up and went out the back door, while I went out the front.
Truman Capote: More tears are shed over answered prayers than unanswered ones.
Truman Capote: Ever since I was a child, folks have thought they had me pegged, because of the way I am, the way I talk. And they're always wrong.
Truman Capote: I have 94 per cent recall of all conversation. I tested it myself.
[last lines]
Truman Capote: And there wasn't anything I could have done to save them.
Nelle Harper Lee: Maybe not. But the fact is, you didn't want to.
Truman Capote: On the night of November 14th, two men broke into a quiet farmhouse in Kansas and murdered an entire family. Why did they do that? Two worlds exist in this country: the quiet conservative life, and and the life of those two men - the underbelly, the criminally violent. Those two worlds converged that bloody night.
Truman Capote: Perry, I know what 'exacerbate' means.
Perry Smith: Okay... well...
Truman Capote: There is not a word or a sentence or a concept that you can illuminate for me.
Perry Smith: I thought that Mr. Clutter was a very nice gentleman. I thought so right up to the moment that I cut his throat.
Perry Smith: [of Hickok] He's naturally mendacious. Not to be trusted. If he had a hundred dollars he'd steal a stick of chewing gum.
Truman Capote: Sometimes when I think of how good my book is going to be, I can't breathe.
Truman Capote: It's the hardest when someone has a notion about you and it's impossible to convince them otherwise.
Truman Capote: I had lunch with Jimmy Baldwin the other day.
Party date: How is he?
Truman Capote: He's lovely, he's a lovely man. And he told me the plot of his new book. And he said, "I just wanted to make sure it's not one of those problem novels," you know. And I said , "Jimmy. Your book is about a Negro homosexual who's in love with a Jew. Wouldn't you call that a problem?"
[everyone laughs]
Nelle Harper Lee: How did you like the movie?
[referring to To Kill a Mockingbird]
Truman Capote: [Muttering after she wanders off] I don't see what all the fuss is about.
Warden Marshall Krutch: You know, I didn't know where to count your boy at first... him being half-Indian. But I did him a favor. I counted him as a white man.
Truman Capote: You're a kind and generous man.
Truman Capote: God, I'm glad you agreed to come. You're the only person I know with the qualifications to be both a research assistant and a personal bodyguard.
Nelle Harper Lee: Thank you.
Truman Capote: If I leave here without understanding you, the world will see you as a monster. Always. And I don't want that.
Nelle Harper Lee: You paid him to say that.
Truman Capote: How did you know?
Truman Capote: It's the book I was always meant to write.
William Shawn: This book will change how people write.
[last title cards]
Title card: _In Cold Blood_ made Truman Capote the most famous writer in America. He never finished another book.
Title card: The epigraph he chose for his last, unfinished work reads: "More tears are shed over answered prayers than unanswered ones."
Title card: He died in 1984 of complications due to alcoholism.
Truman Capote: Balenciaga!
Truman Capote: [to Perry Smith] We're not so different as you might think.
[first lines]
Laura Kinney: Hello? Nancy?