A widower who realized his only connection to his family was through his wife sets off on an impromptu road trip to reunite with each of his grown children.

Young Man in Diner #1: I'm 94. I keep away from the doctors.
Frank Goode: Boy.
Young Man in Diner #1: I have three children, six grandchildren. They're busy. They're too busy to talk to me. I gotta make an appointment. They got lost some place. They don't need anybody. People changed, life is changed. Today, you shake hands with somebody, you gotta count your fingers to make sure you got five fingers back.
Hooker: You wanna see my leg?
Frank Goode: Wanna see mine?
Rosie: We could just talk to mom.
Frank Goode: Oh, but you couldn't just talk to me?
Rosie: Well she was a good listener, you were a good talker.
Frank Goode: Well so that's good, we made a good team.
[last lines]
Frank Goode: If you would ask me I would have to say in all honesty, Everybody's fine. Everybody's fine.
Colleen: We got ourselves an epidemic going on out there. You know, people eating too much, drinking too much, killing themselves, basically. Making up excuses all along the way. Because facing up to the truth ain't always easy. Man, people like things easy. That's what they're used to. No one likes to get hurt. No. Nobody likes to get hurt.
Amy: I tell you the good news and spare you the bad. Isn't that what mom used to do for you when we were kids?
Frank Goode: [showing photos of his children to a stranger] A million feet of wire to get them where they are today.
Wine Man: Well, we got wines from all over the world. We got, uh, English wines from France, we got Italian wines from all over Europe.
Art Gallery Girl: He used to say that if it wasn't for his dad he never would have become an artist. He said he would have ended up painting walls, and that dogs pee on walls...
[first lines]
Butcher: You Keeping busy?
Frank Goode: Yeah, I've been busy.
Butcher: Busy doin' what?
Frank Goode: Busy in the garden.
Butcher: [wryly] In the garden, you know what, you're missing work, that's what, I can see that.
Frank Goode: No I'm not missing work.
Butcher: Yeah, you miss the buzz and the jokes and the guys, I know that, don't tell me that's not true.