Two drifters, one a gentle but slow giant, try to make money working the fields during the Depression so they can fulfill their dreams.

[last lines]
George: [talking about their dream] We're gonna get a little place.
Lennie: Okay, yeah, we're gonna get a little place and we're gonna...
George: We're gonna...
Lennie: ...have...
George: [Lennie mouths what he says] We're gonna have a cow, and some pigs, and we're gonna have, maybe, maybe, a chicken. Down in the flat, we'll have a little field of...
Lennie: Field of alfalfa for the rabbits.
George: ...for the rabbits.
Lennie: And I get to tend the rabbits.
[George shoots Lennie in the head, Lennie dies; George looks at Lennie sadly, sighs and walks to Lennie, leans down to him; scene cuts to George sitting on train at night again; scene cuts to George remembering his and Lennie's final happy memory as they both toss a bag of flour onto a horse wagon, both look at each other, and walk away happily]
George: Guys like us that work on ranches are the loneliest guys in the world. They ain't got no family and they don't belong no place. They got nothin' to look ahead to...
Lennie: But not us George. Tell about us.
George: ...well, we ain't like that. We got a future. We got somebody to talk to that gives a damn about us. If them other guys gets in jail they can rot for all anybody cares.
Lennie: But not us, George, because I... see, I got you to look after me, but you got me to look after you.
Lennie: You said I was your cousin!
George: That was a lie. If I was a relative of yours, I'd shoot myself.
Curley's Wife: Nobody can't blame a person for looking. See y'around.
[She exits the bunkhouse]
Lennie: She's pretty.
George: Lennie! Listen to me, God damn it! Don't you even look at her! I don't care what she says or what she does, she's a rat trap if I ever seen one.
Lennie: But I wasn't doing nothing.
George: No, but when she was shoving her legs around you weren't looking the other way neither. Keep away from her!
Lennie: I don't like this place.
Slim: A guy don't need no sense to be a nice fella.
Lennie: You damn right, George! You *god* damn right!
George: Go to sleep, Lennie.
Lennie: George?
George: Go to sleep, Lennie!
Lennie: I am sleepin', George.
Slim: You travel around together?
George: Yeah.
Slim: There ain't many guys travel around together. I don't know why. Maybe everybody in the whole damn world's scared of each other.
[first lines]
[George sits on a train on a dark night looking depressed, scene cuts to girl with red dress running through field whimpering as George and Lennie escape from her]
George: [to Lennie] Come on.
[woman continues running in fright as George and Lennie continue running away from her as sergeants on horses with dogs track George and Lennie]
Lennie: George, they're gone. They're gone.
George: [angrily] Come on! Keep moving!
[both keep running as sergeants continue following them]
[Lennie is talking with Crooks, the Stable Buck]
Lennie: The rabbits we're gonna get and I, I get to tend 'em.