While still out to destroy the evil Umbrella Corporation, Alice joins a group of survivors living in a prison surrounded by the infected who also want to relocate to the mysterious but supposedly unharmed safe haven known only as Arcadia.

Albert Wesker: I'm what you used to be. Only better.
[last lines]
Jill Valentine: [to her soldiers] Deployment in T-minus 57 seconds. When you hit the deck, you watch your formation. Take no prisoners and shoot to kill. Total enemy numbers are unknown but will include Umbrealla fugitives and prime targets. Claire Redfield, Chris Redfield and Project Alice. So, people, whatever's waiting for you out there, just know one thing: You are gonna be in for the fight of your lives.
Alice: Please wait.
Albert Wesker: Last words?
Alice: Thank you.
Albert Wesker: For killing you?
Alice: For making me human again.
Alice: [to Wesker] Any last words?
Albert Wesker: [sticks syringe in Alice's neck] How nice to finally meet the real you. Hurts, doesn't it? Well, that's just the start of the bad news. All those powers of yours: Speed, strength, accelerated healing. Well, you can kiss all those goodbye.
Alice: What have you done?
Albert Wesker: The serum I've injected you with is neutralizing the T cells within your body. Put simply, the Umbrella Corporation is taking back its property. You just didn't work out, so you're being recalled.
[first lines]
Alice: [narrating] My name is Alice. I worked for the Umbrella Corporation in a secret laboratory developing experimental viral weaponry. There was an incident. A virus escaped. Everybody died. Trouble was, they didn't stay dead. This was the start of an apocalypse that would sweep the entire world. The men responsible for this disaster took refuge underground and continued to experiment with the deadly T-Virus. They felt secure in their high-tech fortress. But they were wrong.
Crystal: That plane of yours, do you think it could still fly?
Alice: It can fly, but it only seats two.
Crystal: So you take us to Arcadia one at a time.
Luther West: Look, I think she was lucky to land here once. Five or six times would be suicide. No offense.
Alice: None taken.
Albert Wesker: Well isn't this one big family reunion? Chris and Claire Redfield, you've really become quite an inconvenience for me.
Alice: I told you I'd be bringing a few friends.
Albert Wesker: [removes sunglasses] You should have brought more.
Alice: You know I have the strangest feeling I know you.
Luther West: Yeah, I get that a lot. You're a sports fan, huh? Do you like basketball?
Alice: Not really.
Luther West: No? Well, maybe just a fan of fine timepieces.
[they look at a distant rooftop billboard with Luther modeling a luxury wristwatch]
Angel Ortiz: Yeah. Luther here is our resident superstar.
Luther West: Nice landing.
Alice: I think technically it's called crashing.
Albert Wesker: [During Alice Clone battle] Tell security to flood the the main entrance with nerve gas.
Umbrella Sergeant: Sir, our men are still up there.
Albert Wesker: [Wesker shoots the Japanese Umbrella employee in the head] Any more questions?
[Axeman is banging at the gate with its battle hammer]
Claire Redfield: Luther, just shoot that motherfucker.
[Luthor shoots Axeman repeatedly in the head, it keeps banging at the gate]
Luther West: What the fuck is that thing?
Albert Wesker: [Upon expecting Alice to enter his chamber] Well, this is a pleasant surprise.
Alice: Why am I not suprised?
Albert Wesker: You weren't too hard to find. Our satellite system is still operational, and there aren't too many people flying now days. Besides, I always knew you would be drawn to your friends. Loyalty - Highly overrated.
Luther West: We thought they sent you. We've been launching flares for days to get their attention.
Alice: Flares?
[she gives an incredulous smirk]
Luther West: Yeah.
Alice: Who's gonna see flares from Alaska?
Luther West: Alaska?
Angel Ortiz: Alaska?
Alice: Arcadia. I've been there. It's in Alaska. It's a town, or so we thought.
Luther West: A town? I don't think so.
Albert Wesker: The T-Virus brought me back.
[his head jerks, jaws set, chest heaves]
Albert Wesker: But it's so strong. It fights me for control. I thought if I ingested fresh human DNA, I could redress the balance.
Alice: No wonder your crew abandon ship.
Albert Wesker: No matter. Now I have a new subordinate. And a new plan. You were the only one who successfully bonded with the T-Virus. Your DNA is stronger than the others. I ingest you, I gain control.
Alice: [nods, walks a few paces to a table] That's pretty smart thinking. There's only one problem with that plan.
Bennett: [aiming gun at Alice] Stop right there.
Albert Wesker: And what is that?
Alice: I'm not on the menu.
[she kicks a tray of surgical instruments at Wesker and takes out Bennett's gun with a roundhouse kick. Wesker dodges the scalpels that impale his chair]
Claire Redfield: Alice, you were my friend?
Alice: I like to think so.
Claire Redfield: Was I a good person?
Alice: Why would you ask that?
Claire Redfield: I don't know, I just, I have this feeling that I let people down.
Alice: You're not the only one.
Claire Redfield: What do you mean?
Alice: We struggle, we fight, we watch our friends die. Survival is a bitch.
Alice: Just don' t do anything crazy, all right?
Claire Redfield: Nothing as crazy as what you have in mind.
Alice: Umbrella.
Claire Redfield: Of course. I remember them coming for us.
Alice: This whole thing, Arcadia, was a lie.
Claire Redfield: No, it's worse than that. It's a trap.
Sniper #1: [kills female undead] Bio-hazard terminated. Central Shibuya. Confirm?
Sniper #2: I confirm. Nice shooting.
Sniper #1: And I lead three to one.
Sniper #2: The night is still young.
Chris Redfield: Claire?
Claire Redfield: What?
Chris Redfield: Claire, it's me. It's Chris.
[Chris caresses her cheek, Claire grabs his arm and twists it behind his back]
Claire Redfield: I don't know you.
Chris Redfield: Claire. I'm your brother, remember? What the hell's happened to you?
Alice: Hey. It's okay. Let him go.
[Claire releases his arm]
Alice: Look, she suffered some sort of memory loss. If you really are her brother, it'll come back.
Alice: [after checking the armory and weapons room] Nice!
Luther West: That's right. Star power, bitches.
Alice: You don't look very good, Bennett.
Bennett: Yeah, I'm looking forward to playing with your pretty face.
Alice: Hey, boys. Is that anyway to treat a lady?
Luther West: [after Bennett steals the plane and drives it off the building edge] That's right, bitch. Fuck you.
Alice: Day 6, 1800 hours, Los Angeles. No signs of life, not even the undead. They must have burned with the city. But what about the rest?