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Alice awakes in Raccoon City, only to find it has become infested with zombies and monsters. With the help of Jill Valentine and Carlos Olivera, Alice must find a way out of the city before it is destroyed by a nuclear missile.
L.J.: [a Zombie walks in front of his car] GTA, Motherfucker! [he runs over the Zombie, which flips over his car] L.J.: Yeah! Ten points!
Alice: There's something down there. Jill Valentine: Where? Alice: There. Peyton Wells: I don't see anything. Alice: Well, that doesn't alter the fact that there *is* something down there.
Major Cain: Why haven't we taken off? [he reaches the pilot seat, and the "pilot" turns around] L.J.: 'Cause I usually drive a Cadillac! [punches Cain]
[first lines] Alice: My name is Alice. I worked for the Umbrella Corporation, the largest and most powerful commercial entity in the world. I was head of security at a secret high-tech facility, The Hive, a giant underground laboratory developing experimental viral weaponry. But there was an incident. The virus escaped and everybody died. Trouble was... they didn't stay dead.
Alice: My name is Alice and I remember everything.
Major Cain: This is what we've been waiting for gentlemen. Confirm at 2:18 and 27 seconds the Nemesis Prgoramme is now fully activated.
[Alice and Carlos have their guns pointed at each other, L.J. comes in from behind] L.J.: Don't shoot, don't shoot. He's cool. He made a deal with Dr. Doom, same as you.
Alice: How long ago have you been bitten? Carlos Olivera: Three hours. L.J.: What? Alice: Today's your lucky day. L.J.: [to Carlos] You should have told me you were bit, motherfucker, I'm hanging with you and shit!
Peyton Wells: We find the building with the thickest walls and strongest doors and we barricade ourselfs in, sit tight, wait for help. Alice: There won't be any help. According to Ashford, Umbrella know they can't contain the infection. So at sunrise this morning, Raccoon City will be completely sanitized. Terri Morales: What do you mean by "sanitized"? Alice: A precision tactical nuclear device. Jill Valentine: What yield? Alice: Five kilotons. Jill Valentine: [scoffs] Fuck me.
Major Cain: And now... Now we'll discover which is superior. Fight him. Alice: No. Major Cain: Fight him, or they die. Alice: What makes you think I care?
[after hearing the S.T.A.R.S. planning to take down the Nemesis] L.J.: You motherfuckers is crazy! Look. That big motherfucker got a rocket launcher!
[after Alice realizes Peyton coughs and has a zombie bite injury, she aims her gun at him] Jill Valentine: [points her gun at Alice] Hold it. What do you think you're doing? Alice: He's wounded. The infection's spreading. Peyton Wells: I'm fine. Alice: You should take care of him now. It'll be more difficult later. You know that. Jill Valentine: No. If it comes to that, I'll take care of it myself. Alice: As you wish. [to Peyton] Alice: It's nothing personal. But in an hour, maybe two, you'll be dead. And moments later, you'll become one of them. You'll endanger your friends, try to kill them, probably succeed. I'm sorry. That's just the way it is.
[L.J. walks into a building and is surrounded by 12 S.T.A.R.S. members] L.J.: Shit! Maybe I was safer outside. Get them guns out of my damn face. [a S.T.A.R.S. officer hands him a shotgun] L.J.: Motherfucker, please. Look. [opens up his jacket revealing two gold guns] L.J.: My shit is custom.
Nicholai Sokolov: [to Jill Valentine whilst wrestling with a dog infected with the T-Virus] Save The Girl! I've got this bitch! [sees another dog coming to assist its friend] Nicholai Sokolov: Oh, shit.
Nicholai Sokolov: [Carlos and Nicolai finds a couple of Umbrella supply crates dropped by a helicoper] What is this? Carlos Olivera: [Carlos opens both cases, empty] Looks like, weapon cases. Nicholai Sokolov: [growing irratated] We don't need weapons, we need *evacuation*! [kicks one of the cases] Carlos Olivera: These weren't meant for us.
[after spotting a zombie in the crowd] Major Cain: It's here. It's reached the gate.
Jill Valentine: Angela Ashford, huh? That's a pretty grown-up name for a little girl. Angie Ashford: I'm not a little girl. Besides... all my friends call me Angie. Jill Valentine: Angie, huh? I like that.
Major Cain: [to Alice] You're not mutation, you are evolution.
Angie Ashford: Are you all right? Dr. Isaacs: [a moment later] Program Alice activated. Jill Valentine: What did they do to you?
Major Cain: I'm surprised there's anyone left alive. Tech #2: They're S.T.A.R.S. Special Tactics and Rescue Squad. They're the best. Major Cain: Let's see how good they really are.
Sniper: I got the power.
Major Cain: Now, finish this. Put him out of his misery... And come with me. Alice: No. Major Cain: You're such a disappointment to me.
Jill Valentine: [after Alice kills the Lickers] Who the fuck are you?
Alice: [after hiding out from zombies in the cemetery!] There's too many of them. Let's get out of here...
[to Terri, on how to kill a zombie with a gun] Jill Valentine: Try to shoot 'em in the head.
Carlos Olivera: [having been bitten by a zombie] This Wound... It won't stop bleeding.
Sniper: [after taking out a zombie] Yaaahoooo! Plenty to go 'round. L.J.: [L.J. comes into the picture looking to steal a vehicle. The sniper and L.J. then spot each other and the sniper appears to shoot at him] DON'T SHOOT! [Instead the sniper takes out another zombie creeping up behind him] L.J.: Thank You!... Owe you one man! Sniper: [Bragging] I got the power!
Spokesperson: [during credits] This is a part of the Umbrella Corporation. Our business is life itself. Some side effects may occur.
Carlos Olivera: We're assets, Nicholai. Expendable assets... and we've just been expended.
L.J.: Somebody get this ugly bitch off of me!
Carlos Olivera: [throws a knife which hits an enemy guard getting up behind Alice] You missed one.
Peyton Wells: What's that you got there? Terri Morales: [shows her camcorder] My... Emmy. That's if any of us make it out of here.
Major Cain: [as Alice prepares to throw him out of the helicopter] Wait! Killing me won't make things right. Alice: No, but it's a start!
Major Cain: [to Alice, referring to her and the Nemesis] The two of you showed such promise, but we had to see you in action. And most impressive you've been. You're like brother and sister. Heightened speed, strength, agility, the same killer instincts. Parallel strands of research. And now... we discover which is superior.
[during a zombie outbreak in the Police Station] Jill Valentine: I'm leaving town, and I suggest you all do the same.
Yuri Loginova: Bite this. [he throws a grenade into an alley full of zombies]
[last lines] Dr. Isaacs: Program Alice activated. Jill Valentine: What did they do to you?
Major Cain: The infection is spreading faster than anyone could have anticipated.
Major Cain: I was instructed to get you and the other scientists out of the hot zone. You're too important to Umbrella to be at risk. Dr. Ashford: I'm not leaving without my daughter. Major Cain: I'm sorry, truly. But the city is sealed. She may have survived the crash, but we couldn't find her anywhere. Even if she were still alive, I couldn't let her out. The risk of infection is too great. You must understand. Dr. Ashford: You do what you have to do. I'm staying.
Carlos Olivera: They're gonna kill her! Take us down now! Chopper Pilot #1: She's a civilian. We have orders. Carlos Olivera: Fuck orders!
Jill Valentine: Those were some pretty slick moves back there. I'm good, but I'm not that good.