After an acrimonious break up, the Mystery Inc. gang are individually brought to an island resort to investigate strange goings on.

Mary Jane: I'm Mary Jane.
Shaggy: Like, that's my favorite name.
[Scooby accidentally hits Shaggy in the face while displaying karate movements]
Shaggy: Hey, Hong Kong Fooey. Watch the fists of fury.
Creature: I've gotta bag of... uh... hamburgers for you. All you have to do is to come out into the dark shadowy part of the woods where no one can see you
Scooby Doo: Okay.
Fred: This is more embarrassing than the time you started cleaning your beans at Don Knotts' Christmas party.
Shaggy: Gee, Scraps, you didn't have to freak out like a jerk and kill all humanity.
Scrappy Doo: And I would have gotten away with it too if it wasn't for you meddling sons of...
[door closes]
Shaggy: [in Daphne's body] Oh, Daph. What's wrong with you? Don't you ever eat?
Shaggy: Hey, you guys, look. I know I'm just the dude that carries the bags, but it seems to me we all play an important part in this group. I mean, we're just like a big, delicious banana split. Fred, you're the big banana; Daphne, you're the pastrami and bubble gum-flavoured ice cream; and Velma, you're the sweet-and-sour mustard sauce that goes on top.
Scooby Doo: Mmm-mm.
Shaggy: That sounds pretty good, doesn't it?
Velma: You know what, Shaggy? You've really put it into perspective for me.
Shaggy: Thanks.
Velma: I quit!
Shaggy: NO!
Daphne: No way! You... you can't quit! I was gonna quit in, like, two seconds! And now everyone is gonna totally think I copied off the smart girl!
Fred: Now, wait a minute. wait a minute. Maybe I quit. I do. Yeah, I quit!
Velma: I'm outta here!
Daphne: Good riddance.
Shaggy: Don't... no! Don't go. Come on, guys, don't do this! Please, don't go.
Scooby Doo: Do I quit?
Shaggy: No, Scoob... friends don't quit. Well, it looks like it's just you and me for a while, buddy, old pal.
Daphne: I'm not helpless. I'm not helpless. I am helpless. I'm gonna die.
Shaggy: Sit grandma, bad grandma, don't eat the kitty.
Velma: I know you. All you care about are swimsuit models.
Fred: Look, I'm a man of substance. Dorky chicks like you turn me on, too.
Fred: [in Daphne's body] Hey! I can look at myself naked!
Velma: Oh brother.
Shaggy: Who's your best buddy?
Scooby Doo: Raggy.
Shaggy: That's right. And who's my best buddy in the whole wide world?
Scooby Doo: Rooby Doo.
Fred: Yo-Yo the bi-atch was like what? And I was like layta on.
Shaggy: Fred.
Fred: Yo. What up, dawg?
[to Scooby]
Fred: And, uh... dog?
Scooby Doo: Keepin' it real.
Fred: Scrappy, I told you no urinating on Daphne.
Scrappy Doo: It was an accident!
Fred: You were marking your territory!
[Deleted scene]
Daphne: [Chained up to a giant stone] you snuck up on me you jerk,let me out.
Daphne: [giant mechanical arm head towards her] This can't be good. No,no,no
[arm enters her body]
Daphne: no,
[arm pulling out her protoplasm]
Daphne: NO!
Daphne: [Protoplasm form] hey,give me back my spirit thingy. This is so uncool, and you're messing up my hair.
Zarkos: [laughs]
Daphne: [to Zarkos] You're a jerk, capital J E R
[enters protoplasm vat]
Velma: Oh please. You get kidnapped so much you should come with your own ransom note.
[Daphne snatches Velma's glasses off her face]
Velma: My glasses. Where's my glasses?
Daphne: Who's helpless now?
Scooby Doo: Raggy, you're rhipped.
Shaggy: I'm whipped? why don't you say that to my face, man?
Scooby Doo: Rokay, I rill! Your rother eats rat roop!
Shaggy: No, Scooby-Doo! YOUR mom eats cat poop!
Zarkos: [Holding Daphne over his back] Captured again, seƱorita.
Daphne: [grunting] Not this time!
[Bites Zarkos's hand]
[trapped in hot dogs]
Scooby Doo: What now?
Shaggy: Let's do what we do best Scoob, eat.
[Scooby bites one]
Scooby Doo: It's plastic.
Shaggy: What do you care? You drink out of the toilet.
Scooby Doo: So do you.
Daphne: [in Fred's body] Fred keeps touching me.
Shaggy: Hey buddy.
Fred: Shaggy... listen man,someone must have spiked my root beer last night. Talk me down man,talk me down.
Shaggy: Fred,you're a freakin' protoplasmic head.
Fred: I know. But I'm still the best looking protoplasmic head here,I mean.
Velma's Friend: [about Scrappy] "Puppy power", huh?
Velma: [laughing] And he wasn't even a puppy. He had a gland disorder.
Daphne: Hey, I'm me again.
Velma: [in Fred's body] Yippee for you.
Shaggy: [as Velma] Man! Like why am I wearing a dress?
Fred: Man, we got beats like it was the lizniz on earth, ya know what I'm sayin', G?
Shaggy: [nods, pauses] No.
Island Emissary: My employer would like you to solve a mystery on Spooky Island.
Shaggy: Hold on, Man. We don't go anywhere with 'scary', 'spooky', 'haunted', or 'forbidden' in the title.
Scooby Doo: Ror rydrocoronic.
Shaggy: Right,or hydroclonic, but that's for a whole different reason, man.
Velma: Daphne? Are you okay?
Daphne: I am so over this damsel in distress nonsense.
Fred: Uh, where's Shagster?
Shaggy: Like, I'm right here, man.
Scooby Doo: Me too.
Shaggy: Hey, Scoob, that was fun. Let's grab another skateboard and, like, do it again,man.
Scooby Doo: Yeah.
Scrappy Doo: Scrappy-Dappy-Doo!
Scooby Doo: Hey!
Scrappy Doo: Ghosts don't stand a chance with me! Let me at em. I'll rock 'em and sock 'em.
Fred: Scrappy, for the thousandth time, there's no such things as ghosts!
Scrappy Doo: Sure there are, and when I find them I'll give them a good of puppy power!
[Urinates on Daphne]
Scrappy Doo: Ta-da!
Daphne: Oh God. He's peeing on me!
Daphne: Those creatures are taking over the world? That is so mean.
Daphne: Now, who's the damsel in distress?
Zarkos: Me?
Daphne: Straight up.
Velma: What's the problem, exactly?
Mondavarious: I believe somebody is casting a spell on the students. Now listen and look around. Can you notice any difference between those arriving and those departing?
Daphne: They look like sober, well-behaved college kids.
Mondavarious: Precisely. And they didn't before they came. They've changed. In other words, a magic spell.
Voodoo Maestro: Whatever you do, don't go into that spooky island castle.
[points to castle]
Daphne: AH-HA, you want me to go into that castle!
Voodoo Maestro: Didn't you hear what I just said?
Daphne: But you're scary and you knew I'd do the opposite of what you said so you told me not to go up to that castle so I would go up to that castle where you've set a trap to capture me.
[thinks for a second]
Daphne: Unless... unless you knew I'd figure it out so you told me not to go up to that castle so I would think that you wanted me to go so I wouldn't go just like you didnt want me to... I'll find out what your hiding in that castle. You'll see.
[Daphne walks away]
Voodoo Maestro: [to himself] What in the world...?
Daphne: I've got this. I've got this.
[Door closes]
Daphne: I don't got this.
Shaggy: Like chill out, Scooby-Doo, stop shaking.
Scooby Doo: Me? That's you.
Shaggy: Oh right it's me, sorry.
Bartender: I got a call here for a Mister Doo? I got a call for Mister Doo.
Melvin: [Stands up] Uh, Melvin Doo?
Bartender: Nah. Scooby.
[Shaggy pulls Daphne's protoplasm out of the vat]
Daphne: Put me back, Shaggy. I'll figure a way out myself.
Shaggy: Like how?
Daphne: I don't know. I'll - I'll use my tongue as an oar to swim to the edge.
Shaggy: Sorry.
[releases Daphne's protoplasm]
[From trailer]
Velma: Scooby doo. Your name means scooby poop.
Velma: Kinda makes you nostalgic for the homicidal creatures, doesn't it?
Daphne: Wait. I know how to deal with this guy.
[shouts to Voodoo Maestro]
Daphne: Hey you! What are you doin'?
Velma: Yes, that is masterful.
Scooby Doo: Why's Fred in a bad mood?
Shaggy: He's not in a bad mood, Scoob, he's a monster.
Fred: How many times do I have to tell you? There is no such thing as ghouls, ghosts, goblins or monsters! Listen up, there is absolutely ABSOLUTELY NO SUCH THING AS...
[monster bursts through glass behind him]
Fred: The prince's got his groove on.
Daphne: I'm looking for clues behind the strange behavior of the college students.
Voodoo Maestro: Well, here's a clue for you: Purple is a fall color. It's the middle of May!
Scrappy Doo: I'm as cute as a Powerpuff Girl. I'll get my own show.
Shaggy: [to Daphne] Like, Scoob and me don't do castles.
Daphne: And why not?
Shaggy: Because castles have paintings with eyes that follow,suits of armor that you think are a statue,and a that keeps following you every time you turn around.
[Talking to Fred and Velma]
Daphne: I'm a black-belt now. I've transformed my body into a dangerous weapon.
Velma: Let's get jinky with it.
Shaggy: Zoinks! them peppers is like hot!
Shaggy: Please tell me you guys are you...
Shaggy: Reminds me of the time we tried to eat the guy in the hot dog costume.
Velma: I'm gonna solve this one first.
Fred: Not before I solve it first.
Daphne: You guys are going to look like total,total idiots when you're captured and I'm the one saving you.
Mondavarious: Well done.
Velma: [to a monster] You could use a little sunlight.
Shaggy: Scooby-Doo, where are you?
Fred: Mr. Mononucleosis, we have hit a clue smorgasboard.
Scooby Doo: What's that?
Mondavarious: It's a cat with a bobbing head, please don't touch it.
Daphne: I've got a major wedgie.
Scooby Doo: Ramburgers.
[Being chased by monsters]
Shaggy: This is, like, the opposite of what I wanted to do today.
[Talking to Scooby Doo]
Shaggy: The only thing I like better than an eggplant burger is a chocolate covered eggplant burger.
Fred: I'm me!
Daphne: I'm back.
Shaggy: Like, me too.
Velma: Told you so.
Bartender: [to Velma] "Nice Sweater."
Zarkos: [while grabbing Daphne and throwing her on his knee] Ah Ha! Damsel in Distress!
Daphne: Let go of me! Help!
Daphne: [to shaggy and scooby] We're here to solve a mystery.

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