Picking up directly from the previous film, vampire warrior Selene and the half werewolf Michael hunt for clues to reveal the history of their races and the war between them.

On Screen Text: [first lines, the text that appears on screen] Eight centuries ago, unknown to humanity, a blood feud raged between a ruling class of vampires and a rebellious legion of werewolves known as Lycans.
On Screen Text: Legend tells that the war began with two brothers, the immortal sons of Alexander Corvinus:
On Screen Text: Markus, bitten by bat, became the blood leader of the vampires.
On Screen Text: William, bitten by wolf, became the first and most powerful Lycan.
Alexander Corvinus: For centuries I've stood back and watched the havoc my sons have wrought on each other, and on humanity - not the legacy I prayed for the morning I watched them enter this world... And it's been a tiresome duty - keeping the war contained, cleaning up the mess, hiding my family's unfortunate history.
Michael Corvin: Couldn't you have stopped it?
Selene: Yes!
Alexander Corvinus: Could you kill your own sons?
Selene: You know what Marcus will do! If he finds me, he finds William's prison! You have to help us stop him!
Alexander Corvinus: You are asking me to help you kill my son - YOU, a Death Dealer? How many innocents have YOU slain in your six-century quest to avenge your family? Spare me your self-righteous declarations! You are no different from Marcus and even less noble than William - at least HE cannot control his savagery!
Selene: Everything I've done can be laid at YOUR feet - hundreds of thousands have died because of your inability to accept that your sons are monsters, that they CREATE monsters!
Marcus: Tanis, you seem anxious. Why do you flee at the very sight of me?
[Sits in a chair calmly]
Marcus: Please, sit. There's no need for this to be unpleasant. I've always rather enjoyed your company.
[Tanis glances at his guns and ultraviolet ammunition, obviously contemplating making a grab for one. Marcus notices this]
Marcus: Now you're being rude.
Tanis: Sorry.
[sits nervously]
Selene: For six centuries I was a loyal soldier to the vampire clan. But I was betrayed. The war was not as it had seemed. In one night, the lies that had united our kind had been exposed. Kraven, our second-in-command, had formed a secret alliance with Lucian, leader of the werewolf clan, to overthrow Viktor, our leader. But Kraven's lust for power and domination had failed. Viktor was not the savior I had been led to believe. He had betrayed us all. Soon, the hunt will be on for his killer. I have but one ally left: Michael, the human descendent of Corvinus. Neither vampire nor lycan, but a hybrid. It's only a matter of time before we're found. My only hope now is to awaken Markus, our last remaining elder, and expose the truth before Kraven tries to murder him while he's still in hibernation. Kraven knows he's no match for him awake.
Selene: You're Alexander Corvinus...
Alexander Corvinus: There was a time when I was known by that name... by any name, I am still your forefather.
[from trailer]
Tanis: You don't scare me, Selene.
Selene: Well, we'll have to work on that.
[Marcus has Kraven pinned to the wall by his talons]
Kraven: Marcus?
Marcus: The blood memories of this wretched creature...
[indicates Singe's body]
Marcus: ...have shown me that your treachery knows no bounds.
Kraven: My lord, I can explain.
Marcus: Why would I listen to your lies when the journey to the truth... is so much sweeter?
[Marcus bites into his neck, and see's visions of Kraven's past, including his bargain with Lucian and Selene killing Viktor]
Kraven: Please. I can assist you.
Marcus: [smiles] Oh, you already have.
[he pulls his talons free, then swipes Kraven's head off.]
Selene: [picks up the abandoned bra of one of Tanis's girlfriends] Your exile seems a bit more comfortable than I remember.
Selene: What will I become?
Alexander Corvinus: The future.
Selene: [to Michael] There's never been a hybrid before. However ambivalent you might feel about it, the truth is, your powers could be limitless. You depend on blood.
[first lines]
Marcus: My God. Brother, what have you done?
Tanis: [after shooting at Selene] I knew it was you Selene. The stench of Viktor's blood still lingers in your veins.
[William has been shot through his limbs by chains, and dragged to the ground. Marcus comes back unexpectedly.]
Viktor: Marcus!
Marcus: He was not to be harmed. Place him in my charge, as we agreed, or you will pay for your deceit.
Viktor: And you will learn your place. Your sympathy for this beast is foolish. Your brother is entirely beyond control. It will be done *my* way.
Marcus: You know well the consequences if your murder me. Or William.
Viktor: If you so much as speak his name again you will have chosen that future for him.
[Marcus looks to his sides - Viktor's warriors have their crossbows poised at him.]
Marcus: What is thy will... my lord?
Viktor: Imprisonment for all time. Far from you.
Michael Corvin: [to the Armed Officers] Get the fuck away from me.
Marcus: Hello Father.
Alexander Corvinus: You are unwelcome in my presence.
Marcus: Ah. The predictable heart that never thaws. Pity it beats within such a fool. The eldest of the immortals, yet you have made no attempt to seize your destiny.
Alexander Corvinus: We are oddities of nature, you and I. Nothing more! This is a world for humanity.
Marcus: And that petty sentiment explains why you rejected your sons? Why you stood by for over half a millennium as William suffered alone in darkness? No, Father, I have no respect for your petty sentiment. Viktor's key. Where is it?
Alexander Corvinus: Whatever plan you have for William is futile. You cannot control your brother.
Marcus: Oh, I am stronger now. And our bond is greater than you have ever wanted to acknowledge.
Alexander Corvinus: You're wrong. Soon you'll be drowning in Lycans just like before.
Marcus: Oh, not Lycans, Father, or Vampires. A new race created in the image of their maker. Their new God. Me.
[Marcus impales Alexander to the wall with his talon]
Marcus: And a true God
[picks up a sword]
Marcus: has no father.
[Marcus drives the sword through Alexander, then takes the key out of his top pocket]
Alexander Corvinus: You will fail.
Marcus: [to Selene] I knew Viktor made a mistake by keeping you as a pet. He should have killed you with the rest of your family.
Marcus: I know what you have done, Selene.
Selene: Viktor deserved his fate. And Kraven was no better.
Marcus: Kraven has already reaped the rewards of his own misdeeds. And yes, Viktor deserved his fate, many times over. A terrible business, the slaying of your mortal family. Yet so much effort was spent to conceal this matter from me. What do you suppose Viktor had to hide? Or perhaps it is you Selene, as the last of your wretched family, who has something to hide?
[William, Marcus Corvinus's twin brother and the very first werewolf, is released from his prison of a thousand years. He growls and charges at Marcus]
Marcus: William... No, William, no! Calm down! Be still, brother... it's me, Marcus!
Marcus: Viktor fashioned two keys. What do you know of them?
Tanis: Keys? I don't know of any keys.
[Marcus spears Tanis in the shoulders and pulls him across the table]
Tanis: Oh... yes. Yes, those keys.
Marcus: [to Selene] Dead or alive, you will give me what I want!
Selene: [glances at Michael] We're not leaving him here.