James Rothman — American Scientist born on November 03, 1950,

James Edward Rothman is an American biochemist. He is the Fergus F. Wallace Professor of Biomedical Sciences at Yale University, the Chairman of the Department of Cell Biology at Yale School of Medicine, and the Director of the Nanobiology Institute at the Yale West Campus. Rothman is also concurrently serving as adjunct professor of physiology and cellular biophysics at Columbia University. and a research professor at the Institute of Neurology, University College, London. Rothman was awarded the 2013 Nobel Prize in Physiology or Medicine, for his work on vesicle trafficking. He has also received many other honors, including the King Faisal International Prize in 1996, the Louisa Gross Horwitz Prize from Columbia University and the Albert Lasker Award for Basic Medical Research both in 2002... (wikipedia)

One of the major lessons in all of biochemistry, cell biology and molecular medicine is that when proteins operate at the sub cellular level, they behave in a certain way as if they're mechanical machinery.
I might have been just as happy to have been a practicing primary-care doctor. But as a medical student, I had interacted with patients suffering from neurodegeneration or acute clinical schizophrenia. It left an indelible mark on my memory.
As physics students, we are taught that physicists are smart, that chemists are moderately acceptable, and that biologists are certainly not very intelligent. So I wasn't inclined to take a biology course. But my father insisted, and maybe what he had in mind was that, if there were no jobs in physics, I would end up being a doctor.
In the earlier years when I started this project at Stanford University, everyone told me it was nuts to go and try to reproduce the mysterious complexities that occur in a whole cell.
I started taking a basic biology course, and I really loved it. I started asking research questions incessantly. I was drawn very quickly to biology.