We don't mind having sanctions banning us from Europe. We are not Europeans.
Opponents of U.S. sanctions have made 'unilateral sanctions' their special target. They argue that sanctions observed by many nations would be much more effective. True enough. Far better for trade with an outlaw regime to be restricted by many nations than by just one.
Sanctions are a bad idea.
People talk about smart sanctions and crippling sanctions. I've never seen smart sanctions, and crippling sanctions cripple everyone, including innocent civilians, and make the government more popular.
Like all forms of collective security, multilateral sanctions require a unanimity rarely achieved in international politics.